Research Archive

3 papers

Date not specified · 1 min read

Perturbation-Resolved Single-Cell CRISPR Mapping of Tumor Immune-Escape Networks Predicts Durable Response to Immune Checkpoint Blockade

Proposed review-derived manuscript investigating tumor immune-escape mechanisms through single-cell CRISPR perturbation mapping, spatial immunology, and predictive response modeling for immune checkpoint blockade. The study synthesizes evidence from CRISPR screens, single-cell profiling, and computational frameworks to identify multicellular immune resistance networks, including T-cell exhaustion, immune exclusion, antigen presentation failure, and myeloid suppression. Lead author: Sadia Tasneem

Date not specified · 1 min read

Women’s Occupational Health, Hygiene Practices, and Healthcare Access Among Garment Workers in Bangladesh

Proposed MPH thesis–derived manuscript examining occupational health risks, reproductive and menstrual-health needs, hygiene practices, and access to healthcare among female garment workers in Bangladesh. Lead author: Dr. Sadia Tasneem. Co-authors, methodology, and study findings will be added after thesis completion and supervisor approval. This topic aligns with her MPH specialization in Reproductive and Child Health and her occupational-health experience in the garment sector.

Date not specified · 1 min read

Immune Metabolic Stress Signatures Predict Beta Cell Failure and Reversibility During Early Diabetes Progression

Proposed integrative biomedical manuscript examining immune-metabolic stress pathways, beta-cell dysfunction, and recovery potential during early diabetes progression. The study explores mitochondrial stress, inflammatory signaling, oxidative damage, endoplasmic-reticulum dysfunction, single-cell multi-omic profiles, and circulating biomarkers associated with reversible and progressive beta-cell failure. Lead author: Sadia Tasneem. Co-authors, methodology, and study findings will be added after